Mesothelioma Chemotherapy

Is considered one of the most chemotherapy treatments used widely in the treatment of cancer patients, and one of the best treatment options that can be effective for patients with mesothelioma.Chemotherapy and help reduce the symptoms of the disease and improve the lives of patients who can not perform surgery.Using chemotherapy to kill cancer cells and prevent them from multiplying and reducing the size of the tumor, there are several different types of chemotherapy drugs for the treatment of mesothelioma will be talking about in detail later, is aimed chemotherapy to target cancer cells
that divide quickly, but can also be detrimental to any cells in the body For example, hair follicles are one of the fastest growing cells and thus be damaged quickly with chemotherapy, leading to a temporary fall of the hair.Chemotherapy is given by injection into a vein or in pill form and knows the name of this kind irregular as it travels through the blood to the entire body.

Chemotherapy drugs to the tumor
You can use a different number of medications in the treatment Akimaa├║y groups of two or more medications, but some patients do not tolerate more than one drug, the most common and widely used drug is meta (pemetrexed) and there are several other types include:
Alimta
Alimta is the first drug that has been specifically approved for the treatment of mesothelioma, a more effective chemotherapy for pleural mesothelioma patients who are not candidates for surgery.And is injected into a vein, usually given once every 21 days and is taken with vitamin b12 and folate to reduce the side effects. Between medications approved recently, Alimta stands out as there are many opportunities in prolonging the lives of mesothelioma patients, as well as improve their lives.
Side effects of Alimta

  • Nausea
  • Fatigue
  • Constipation
  • Diarrhea
  • Vomiting
  • Confusion
  • Loss of appetite
  • Weight loss
  • Fatigue
  • Weakness
  • Headache
  • Dizziness
  • Heart rate
  • Difficulty in sleeping
  • Changes in mood
  • Depression
  • Pain in the muscles
  • Low red blood cells (anemia).

Cisplatin 
Chemotherapy drug cisplatin platinum which is used to treat a variety of cancers, including mesothelioma is often used in combination with other drugs such as Alimta. 
Cisplatin has a relatively low response rate of less than 15% in most reported cases of pleural mesothelioma. However, when combined with other chemotherapy drugs, patients experienced improved response rates. For example, the combination of cisplatin and Alimta (pemetrexed) has become the most effective chemotherapy for patients with a pleural mesothelioma who are not candidates for surgery. It was found that this treatment with treatment to prolong life expectancy and response rates tend to be less than 50%. 


Gemcitabine 
Huahd chemotherapy drugs available to treat mesothelioma, and is often used to treat pancreatic, bladder, breast cancer and certain types of lung cancer. Gemcitabine treatment was introduced to the market by the company Eli Lilly and Company in association with carboplatin. 
Gemcitabine works simply by killing the cells with complex chemical reactions. Gemcitabine can slow the growth of asbestos cancer by killing cancer cells and overlap with existing DNA replication in other cells. 


Carboplatin 
Many doctors prefer to carboplatin because of their side effects less severe compared with chemotherapy. Carboplatin is a modified version of cisplatin, carboplatin given medication through a vein, usually once every 28 days. In cases where the patient with chemotherapy mesothelioma requires more frequent, sometimes is combined with carboplatin treatment with other treatments or drugs, may be administered on the basis of in-patient, and require the establishment of two or more consecutive days in the hospital.Doctors are advised to avoid any person suffering from kidney disease from seeking treatment with carboplatin. Because this drug, like most chemotherapy drugs, and harmful to infants and unborn. And therefore, should pregnant women or nursing mothers do not use this medication.


Side effects of carboplatin
  • Nausea and vomiting
  • Hair loss
  • Fatigue and weakness
  • Loss of appetite

Onconase 
Advantage of this drug that kills cancer cells while preserving healthy tissue of the patient and works to target the cells that divide rapidly to reduce their growth.This medicine is given by injection every week MRO for 30 minutes, this drug was tested in 105 patients, 39 of which previously undergone chemotherapy. Each patient received intravenous Onconase for 30 minutes each week. Overall, the researchers reported times the average survival between six and eight months. Rates of survival were similar or better than staying alive again, such as chemotherapy.


The most common side effect of mesothelioma chemotherapy-related and include:
  • Loss of appetite
  • Constipation
  • Diarrhea
  • Rash
  • Fatigue
  • Anemia (lack of red blood cells)
  • Fever
  • Hair loss
  • Nausea and vomiting
  • Tingling in the feet and hands
  • Less the number of platelets
  • The immune system of risk


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